BD1052 (Redirected from BD-1052)

BD1052
BD1052.png
Identifiers
  • N-[2-(3,4-dichlorophenyl)ethyl]-N-2-propen-1-yl-1-pyrrolidineethanamine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H24Cl2N2
Molar mass327.29 g·mol−1
3D model (JSmol)
  • Clc1ccc(cc1Cl)CCN(CCN2CCCC2)C\C=C
  • InChI=1S/C17H24Cl2N2/c1-2-8-20(12-13-21-9-3-4-10-21)11-7-15-5-6-16(18)17(19)14-15/h2,5-6,14H,1,3-4,7-13H2
  • Key:IKFDBDJFYBCATB-UHFFFAOYSA-N

BD1052 or N-[2-(3,4-dichlorophenyl)ethyl]-N-2-propen-1-yl-1-pyrrolidineethanamine is a selective sigma receptor agonist, with a reported binding affinity of Ki = 2 ± 0.5 nM for the sigma-1 receptor and 30 times selectivity over the sigma-2 receptor.

Consistent with other reported sigma receptor agonists, pretreating Swiss Webster mice with BD1052 significantly increases the behavioral toxicity of cocaine.

See also


This page was last updated at 2022-12-03 08:54 UTC. Update now. View original page.

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