BD1060 (Redirected from BD-1060)
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Formula | C14H20Cl2N2 |
Molar mass | 287.23 g·mol−1 |
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BD1060 or N-[2-(3,4-dichlorophenyl)ethyl]-1-pyrrolidineethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 3 ± 0.1 nM for the sigma-1 receptor and greater than 50 times selectivity over the sigma-2 receptor.
Like other sigma receptor antagonists, pretreating Swiss Webster mice with BD1060 significantly reduces the behavioral toxicity of cocaine.
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