Castoreum

Castoreum /kæsˈtɔːriəm/ is a yellowish exudate from the castor sacs of mature beavers. Beavers use castoreum in combination with urine to scent mark their territory. Both beaver sexes have a pair of castor sacs and a pair of anal glands, located in two cavities under the skin between the pelvis and the base of the tail. The castor sacs are not true glands (endocrine or exocrine) on a cellular level, hence references to these structures as preputial glands, castor glands, or scent glands are misnomers.
It is used as a tincture in some perfumes and, rarely, as a food additive.
Chemical composition
At least 24 compounds are known constituents of beaver castoreum. Several of these have pheromonal activity, of which the phenols 4-ethylphenol and catechol and the ketones acetophenone and 3-hydroxyacetophenone are strongest. Five additional compounds elicit a weaker response: 4-methylcatechol, 4-methoxyacetophenone, 5-methoxysalicylic acid, salicylaldehyde, and 3-hydroxybenzoic acid. There are also oxygen-containing monoterpenes such as 6-methyl-l-heptanol, 4,6-dimethyl-l-heptanol, isopinocamphone, pinocamphone, and two linalool oxides and their acetates. Other compounds are: benzoic acid, benzyl alcohol, borneol, o-cresol, 4-(4'-hydroxyphenyl)-2-butanone, hydroquinone, phenol. All those compounds are gathered from plant food. It also contains nupharamine alkaloids and castoramine, and cis-cyclohexane-1,2-diol.
Uses
In perfume

In perfumery, the term castoreum refers to the resinoid extract resulting from the dried and alcohol tinctured beaver castor. The dried beaver castor sacs are generally aged for two or more years to mellow.
Castoreum is largely used for its note suggesting leather, typically compounded with other ingredients including top, middle, and base notes. Some classic perfumes incorporating castor are Emeraude, Chanel Antaeus, Cuir de Russie, Magie Noire, Lancôme Caractère, Hechter Madame, Givenchy III, Shalimar, and many "leather" themed compositions.
In food
In the United States, the Food and Drug Administration lists castoreum extract as a generally recognized as safe (GRAS) food additive. In 1965, the Flavor and Extract Manufacturers Association's GRAS program (FEMA 2261 and 2262) added castoreum extract and castoreum liquid. The annual industry consumption is very low, around 100 kilograms (300 lb), whereas vanillin is over 1.2×10 6 kg (2.6×10 6 lb) annually.
Castoreum has been traditionally used in Sweden for flavoring a variety of schnapps commonly referred to as Bäverhojt (lit. 'beaver shout').
Other
Castoreum was also considered for use to contribute to the flavor and odor of cigarettes.
Medieval beekeepers used castoreum to increase honey production.
Related animal products
- Taxea, a secretion of the badger's subcaudal glands comparable in its medicinal use to the better-known castoreum
- Hyraceum, the petrified and rock-like excrement composed of urine and feces excreted by the Cape hyrax (Procavia capensis), and a sought-after material that has been used in traditional South African medicine and perfumery