Metepa

Metepa
Names
IUPAC name
1-[Bis(2-methyl-1-aziridinyl)phosphoryl]-2-methylaziridine
Preferred IUPAC name
1,1′,1″-Phosphoryltris(2-methylaziridine)
Other names
Methaphoxide
Metapoxide
Methyl aphoxide
METEPA
Trimethylaziridinylphosphine oxide
MAPO
Tris(1,2-propylene)phosphoramide
Tris(2-methyl-1-aziridinyl)phosphine oxide
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.000.296 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C9H18N3OP/c1-7-4-10(7)14(13,11-5-8(11)2)12-6-9(12)3/h7-9H,4-6H2,1-3H3 checkY
    Key: AVUYXHYHTTVPRX-UHFFFAOYSA-N checkY
  • InChI=1/C9H18N3OP/c1-7-4-10(7)14(13,11-5-8(11)2)12-6-9(12)3/h7-9H,4-6H2,1-3H3
    Key: AVUYXHYHTTVPRX-UHFFFAOYAF
  • CC1CN1P(=O)(N2CC2C)N3CC3C
Properties
C9H18N3OP
Molar mass 215.237 g·mol−1
Appearance Colorless liquid
Boiling point 90 to 92 °C (194 to 198 °F; 363 to 365 K) (0.15-0.3 mmHg)
Hazards
Lethal dose or concentration (LD, LC):
136 mg/kg (male rat, oral)
213 mg/kg (female rat, oral)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Infobox references

Metepa is a chemosterilant, with the capability to restrict ovarian development. Metepa can also result in carcinogenesis, in particular the formation of teratomas. It a minor ingredient in certain solid rocket propellants.


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