O-2172

O-2172
Identifiers
  • methyl 2-cyclopentyl-2-(3,4-dichlorophenyl)acetate
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC14H16Cl2O2
Molar mass287.18 g·mol−1
3D model (JSmol)
  • Clc1ccc(cc1Cl)C(C(=O)OC)C2CCCC2
  • InChI=1S/C14H16Cl2O2/c1-18-14(17)13(9-4-2-3-5-9)10-6-7-11(15)12(16)8-10/h6-9,13H,2-5H2,1H3 ☒N
  • Key:NEHPFNBRZYFWFN-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

O-2172 is a drug developed by Organix Inc, which acts as a stimulant and potent dopamine reuptake inhibitor. It is an analogue of methylphenidate where the phenyl ring has had a 3,4-dichloro substitution added, and the piperidine ring has been replaced by cyclopentane. It is around 1/3 the potency of methylphenidate, demonstrating that even with the important binding group of the nitrogen lone pair removed entirely, selective DAT binding and reuptake inhibition is still possible.

See also


This page was last updated at 2023-07-14 05:22 UTC. Update now. View original page.

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