PRIM1

PRIM1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPRIM1, p49, primase (DNA) subunit 1, DNA primase subunit 1
External IDsOMIM: 176635 MGI: 97757 HomoloGene: 730 GeneCards: PRIM1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000946

NM_008921

RefSeq (protein)

NP_000937

NP_032947

Location (UCSC)Chr 12: 56.73 – 56.75 MbChr 10: 127.85 – 127.87 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

DNA primase small subunit is an enzyme that in humans is encoded by the PRIM1 gene.

The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.



This page was last updated at 2024-02-13 17:56 UTC. Update now. View original page.

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