SLC2A9

SLC2A9
Identifiers
Aliases	SLC2A9, solute carrier family 2 (facilitated glucose transporter), member 9, GLUT9, GLUTX, UAQTL2, URATv1, solute carrier family 2 member 9
External IDs	OMIM: 606142 MGI: 2152844 HomoloGene: 69290 GeneCards: SLC2A9
Gene location (Human)
Chr.	Chromosome 4 (human)
End	10,054,936 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	38,660,486 bp
RNA expression pattern
	Top expressed in
	monocyte; ; kidney; ; right lobe of liver; ; pancreatic ductal cell; ; right lung; ; salivary gland; ; minor salivary gland; ; kidney tubule; ; parotid gland; ; upper lobe of left lung;
	Top expressed in
	connecting tubule; ; jejunum; ; liver; ; secondary oocyte; ; morula; ; distal tubule; ; thymus; ; aortic valve; ; ascending aorta; ; distal convoluted tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transporter activity; carbohydrate:proton symporter activity; glucose transmembrane transporter activity; urate transmembrane transporter activity; transmembrane transporter activity;
Cellular component	apical plasma membrane; basolateral plasma membrane; plasma membrane; membrane; integral component of membrane; nuclear envelope; integral component of plasma membrane;
Biological process	urate metabolic process; carbohydrate transport; transmembrane transport; hexose transmembrane transport; urate transport; proton transmembrane transport; glucose transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	56606
	117591
	ENSG00000109667
	ENSMUSG00000005107
	Q9NRM0
	Q3T9X0
	NM_001001290; NM_020041
	NM_001012363; NM_001102414; NM_001102415; NM_145559
	NP_001001290; NP_064425
	NP_001012363; NP_001095884; NP_001095885; NP_663534
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene.

This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.

SLC2A9 has also recently been found to transport uric acid, and genetic variants of the transporter have been linked to increased risk of development of both hyperuricemia, gout and Alzheimer's disease.

SLC2A9

See also